ABC, with a new boss Paul Lee, is pretty much wiping the slate clean for fall.

It canceled Brothers and Sisters, V, Detroit 1-8-7, Mr. Sunshine, No Ordinary Family, Off The Map and Better With You.

Body of Proof and Happy Endings, two midseason shows, are coming back.

ABC is adding 12 new series — seven dramas and five comedies — to its 2011-12 schedule.

Charlie’s Angels — A modern take on the 1970s series starring Annie Ilonzeh (Melrose Place), Minka Kelly (Friday Night Lights, Parenthood) and Rachael Taylor (Grey’s Anatomy) as Charlie’s (Robert Wagner) new Angels.

Last Man Standing — Tim Allen deals with a world increasingly dominated by women. Nancy Travis (So I Married an Axe Murderer) co-stars. Jack Burditt (30 Rock) wrote the pilot.

Pan Am — A sexy soap about stewardesses and pilots set in the 60s. Some of the characters live double lives as spies. Christina Ricci. Written and produced by Jack Orman (ER).

Apartment 23 — Midwestern girl (Dreama Walker, The Good Wife) moves to New York, where she finds herself living with her worst nightmare (Krysten Ritter, Breaking Bad). James Van Der Beek (Dawson’s Creek) co-stars as himself in his first series comedy role.

Good Christian Belles — A former high school “mean girl” (Leslie Bibb, Popular) returns home to Dallas after her marriage ends in scandal. Kristin Chenoweth (Glee) and Annie Potts (Designing Women) also star.

Revenge –The Count of Monte Cristo-inspired soap from Mike Kelley (Swingtown), centers on a woman (Emily VanCamp, Brothers and Sisters) who moves to the Hamptons.

Once Upon a Time — A fantasy drama that finds a woman (Jennifer Morrison, How I Met Your Mother) drawn into a town where fairy tales might be real. Ginnifer Goodwin (Big Love) co-stars as Snow White.

Scandal — The drama revolves around the life and work of a professional fixer (Kerry Washington) and her staff. Henry Ian Cusick (Lost) co-stars as her right-hand man. Shonda Rhimes is a producer.

The River — A thriller that follows a crew through the Amazon in search of a missing adventurer. Eloise Mumford (Lone Star) stars.

Work It — Shades of Bosum Buddies. In this cross-dressing comedy, two out-of-work car salesmen (Amaury Nolasco, Ben Koldyke) dress as women in order to get jobs as pharmaceutical reps.

Suburgatory — Jane Levy is a New Yorker who moves to a cookie-cutter community and discovers the horror of the suburbs.

Man Up — A look at what it takes to survive as a modern man, as told through the eyes of three best friends and the women in their lives.

ABC, which had plenty of pilots to choose from, passed on Georgetown from Josh Schwartz, Hallelujah from Marc Cherry and Poe, the supernatural police procedural.